BDBM50023198 8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5-yl)-4-oxo-4H-1-benzopyran::CHEMBL21333::N-(4-oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl)-4-(4-phenylbutoxy)benzamide::N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide::N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide (ONO-RS-411)::N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide(ONO-RS-411)::ONO-1078::PRANLUKAST
SMILES O=C(Nc1cccc2c1oc(cc2=O)-c1nnn[nH]1)c1ccc(OCCCCc2ccccc2)cc1
InChI Key InChIKey=NBQKINXMPLXUET-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50023198
Affinity DataKi: 0.800nMAssay Description:Compound was evaluated in vitro for the binding of Cysteinyl leukotriene receptor 1 to guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonism of Cysteinyl leukotriene receptor 1 from guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Ability to antagonize LTD4 receptors isolated from guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at human CysLT1More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity against CysLT1 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization pr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0440nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of cysteinyl leukotriene receptor 1 (unknown origin) expressed in HEK293 cell membranes after 45 mins by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 2.14E+5nMAssay Description:Dissociation constant for CysLT1 receptor was determined by the displacement of [3H]LTD4 from guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0440nMAssay Description:Displacement of [3H]ICI from cysteinyl leukotriene receptor 1 in Hartley guinea pig lung membrane after 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair